(1) The outer layer of the cerebrum , called the cerebral cortex, is responsible for most higher brain functions such as thought, reasoning, memory, and voluntary muscle movement.(2) These changes were observed in a multifocal distribution involving the white matter of the cerebrum , cerebellum, brain stem, and spinal cord.(3) The cortical system of arterial branches ramifies over the cerebrum to supply the cortex with arterioles that anastomose in the pia mater.(4) The cerebrum , pons, and medulla were hypoplastic.(5) When pain is experienced, this sensation has reached the cerebrum through complex and dynamic interactions.